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The Edinburgh Mouse Atlas Project: School Tutorial |
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| The UK MRC Human Genetics Unit in Edinburgh is developing a digital atlas of mouse development. The project is in collaboration with the Department of Anatomy, University of Edinburgh and the Jackson Laboratory (USA). | |||
| The basic idea is to build a digital model of
the mouse embryo for each time step (stage) in development. Each model embryo
will then be used as a framework or "database" into which results from many
experiments can be mapped. In this way, experimental data can be
stored and compared to find important relationships. The sort of
information that will be mapped will be in situ
gene expression (places where genes are active) and cell lineage
(where tissues come from and what they become). Information from
experiments done in many different laboratories will be mapped to the same
model embryos. This will make sure that the information is
accessible to all scientists so as to minimise the need for more experiments.
In these pages you can browse through the various aspects of this project, how we are trying to solve the biological and technical problems and some of the results so far. To find out how we are building the atlas, click with the left mouse button on any of the links shown in blue (or red if you have already visited that page). You can also click on some of the images to get bigger versions or sometimes movies. Use the "back" button on the browser (top bar if you are using netscape) to return to earlier viewed pages. |
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Dr. D. R.
Davidson &
Dr. R. A. Baldock
(MRC project leaders) Dr. J. B. L. Bard & Prof. M. H. Kaufman (Dept. Anatomy) Dr. Richard Baldock (Web/DB problems) |
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