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EMAGE:1255

Tbx6 T-box 6 ( MGI:102539)
TS12 (8.5 dpc)
in situ hybridisation

Data Images
EMAGE:1255 EMAGE:1255
Figure 3C of Xue et al., 2001 [PMID:11290295] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright. Figure 3D of Xue et al., 2001 [PMID:11290295] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
C - lateral view, D - dorsal view.
Expression Pattern Description
Spatial Annotation:
EMAGE:1255Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
1255_wholemount_strong_3D_1.wlz
1255_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:1255_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
primitive streak
detected detected
Expression in cells adjacent to the primitive streak.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:33996
Entity Detected:Tbx6, T-box 6 ( MGI:102539)
Notes:The Tbx6 probe used in this study by Xue et al., 2001 [PMID11290295] was previously described by Chapman et al., 1996 [PMID:8954725] as "consisting of approximately 1150 bp of the Tbx6 cDNA, including part of the T-box region." The sequence of the Tbx6 gene is given in Genbank U57331.1, however the exact endpoints of the probe are unknown.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:Swiss Webster
Age:8.5 dpc
Theiler Stage:TS12
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Xue et al., 2001 [PMID11290295] Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11290295] Xue Y, Wang X, Li Z, Gotoh N, Chapman D, Skolnik EY 2001 Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK). Development (128):1559-72
 [ doi:10.1006/dbio.1996.0326] [ PMID:8954725] Chapman DL, Agulnik I, Hancock S, Silver LM, Papaioannou VE 1996 Tbx6, a mouse T-Box gene implicated in paraxial mesoderm formation at gastrulation. Dev Biol (180):534-42
Links:MGI:1933086 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI