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EMAGE:4720

Nodal nodal ( MGI:97359)
TS18 (10 dpc)
in situ reporter

Data Images
EMAGE:4720
Figure 5E. Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2006.02.002] Dev Biol 2006 May 15;293(2):370-81, Andersson O; Reissmann E; Jornvall H; Ibanez CF, "Synergistic interaction between Gdf1 and Nodal during anterior axis development." Copyright 1995 [PMID:7556909] .

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: arrow, first branchial pouch at the border between the first and the second branchial arches. ba1, first branchial arch.
Expression Pattern Description
Spatial Annotation:
EMAGE:4720Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4720_wholemount_notDetected_3D_1.wlz
4720_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4720_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
1st branchial pouch
detected detected
regionalExpressed in the first branchial pouch at the border between the first and the second branchial arches.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Nodal, nodal ( MGI:97359)
Notes:Nodal expression in this study by Andersson et al, 2006 [PMID:16564040] was assayed using embryos heterozygous for a targeted insertion, first described by Collignon et al, 1996 [PMID:8610012] . A 400 bp segment from the second exon was replaced with an IRES-lacZ and neomycin gene fusion cassette. Beta-galactosidase was expressed from this allele under the control of the endogenous promoter.
Labelled with:LacZ
Specimen
Organism:mouse
Strain:(involves: 129S/SvEv)
Age:10 dpc
Theiler Stage:TS18
Mutations:Nodaltm1Rob/Nodal+
Preparation:wholemount
Procedures
General Information
Authors:Andersson O; Reissmann E; Jornvall H; Ibanez CF, 2006 [PMID:16564040] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.ydbio.2006.02.002] [ PMID:16564040] Andersson O, Reissmann E, J�rnvall H, Ib��ez CF 2006 Synergistic interaction between Gdf1 and Nodal during anterior axis development. Dev Biol (293):370-81
 [ doi:10.1038/381155a0] [ PMID:8610012] Collignon J, Varlet I, Robertson EJ 1996 Relationship between asymmetric nodal expression and the direction of embryonic turning. Nature (381):155-8
Links:MGI:2180793 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE