EMAGE mouse gene expression spatial database

EMAGE:3434

Nkx2-1 NK2 homeobox 1 ( MGI:108067)
TS17 (10.5 dpc)
immunohistochemistry

Data Images


Figure 1G of Corbin et al., 2003 [PMID:12930780] . Copyright: This image is from Corbin et al., Development 130, 4895-4906 (2003), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.	Figure 1I of Corbin et al., 2003 [PMID:12930780] . Copyright: This image is from Corbin et al., Development 130, 4895-4906 (2003), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

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Notes:

Note: Pax6 expression in green, Nkx2.1(Titf1) expression in red, Gsh2 expression in blue. Arrow, gap between Pax6 and Nkx2.1 [Titf1] expression.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

3D mapping

spatial mapping

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Text Annotation:

Structure

Level

Pattern

Notes

telencephalon

detected

regional

Gap in expression of Pax6 and Nkx2.1 [Titf1] expands.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	antibody
Identifier:	MGI:2676172
Entity Detected:	Nkx2-1, NK2 homeobox 1 ( MGI:108067)
Notes:	The anti-Titf1(Nkx2.1) antibody used in this study by Corbin et al., 2003 [PMID:12930780] was either a "mouse anti-Nkx2.1 (1:2000, DAKO, CA, USA)" or a "rabbit anti-Nkx2.1 (1:150, Biopat, Italy)". It is unspecified which of these were used in this actual experiment.
Antibody Type:	monoclonal

Specimen

Procedures

Fixation:	4% paraformaldehyde
Embedding:	cryosection

General Information

Authors:	Corbin JG; Rutlin M; Gaiano N; Fishell G, 2003 [PMID:12930780] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1242/dev.00717] [ PMID:12930780] Corbin JG, Rutlin M, Gaiano N, Fishell G 2003 Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development (130):4895-906
Links:	MGI:2676233 same experiment
	EMAGE:3379 same section & embryo
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source