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EMAGE:3632

Crabp1 cellular retinoic acid binding protein I ( MGI:88490)
TS20 (12.0 dpc)
immunohistochemistry

Data Images
EMAGE:3632
Fig 1B bottomCopyright: Reprinted with permission from Elsevier from [doi:10.1006/dbio.1993.1197] Dev Biol 158: 390-9, McCaffrery P; Posch KC; Napoli JL; Gudas L; Drager UC, Changing patterns of the retinoic acid system in the developing retina. Copyright 1993

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:3632EMAGE:3632Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mappingspatial mapping

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
3632_voxel_strong_3D_1.wlz
3632_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3632_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
optic stalk
detected detected
regionalExpression is in the vitreal margin, in a central region slightly temporal and dorsal to the optic disc. The cells project axons into the optic stalk.
retina
detected detected
regionalExpression is in the vitreal margin, in a central region slightly temporal and dorsal to the optic disc. The cells project axons into the optic stalk.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:antibody
Identifier:MGI:2156788
Entity Detected:Crabp1, cellular retinoic acid binding protein I ( MGI:88490)
Antigen:sense strand is shown

>MGI:2156788
LTFGADDVVCTRIYVRE
aa 121 - aa 137 of P62965
Notes:The production of the antibody used in this study by McCaffrery et al., 1993 [PMID:8393814] is described as follows, "The peptide sequence (given above (i.e. LTFGADDVVCTRIYVRE)) from the carboxy-terminal end of the murine CRABP I protein (Stoner and Gudas, 1989 [PMID:2538228] ) was coupled to either KLH or thyroglobulin and injected intramuscularly into guinea pigs."
Antibody Type:polyclonal
Raised In:guinea pig
Specimen
Organism:mouse
Age:12.0 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Embedding:cryosection
Visualisation method:fluorescence
General Information
Authors:McCaffrery P; Posch KC; Napoli JL; Gudas L; Drager UC, 1993 [PMID:8393814] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1006/dbio.1993.1197] [ PMID:8393814] McCaffrery P, Posch KC, Napoli JL, Gudas L, Drager UC 1993 Changing patterns of the retinoic acid system in the developing retina. Dev Biol (158):390-9
 [ PMID:2538228] Stoner CM, Gudas LJ 1989 Mouse cellular retinoic acid binding protein: cloning, complementary DNA sequence, and messenger RNA expression during the retinoic acid-induced differentiation of F9 wild type and RA-3-10 mutant teratocarcinoma cells. Cancer Res (49):1497-504
Links:MGI:2156791 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI