Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:3892

Wnt1 wingless-related MMTV integration site 1 ( MGI:98953)
TS15 (25 Somite no.)
in situ hybridisation

Data Images
EMAGE:3892
Figure 2H. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S1567-133X(03)00087-5] Gene Expr Patterns 3: 397-405, Zhou XH; Brandau O; Feng K; Oohashi T; Ninomiya Y; Rauch U; Fassler R, The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain. Copyright 2003.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: Dorsal midline of the midbrain (dml), spinal cord (arrow).
Expression Pattern Description
Spatial Annotation:
EMAGE:3892Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
3892_wholemount_strong_3D_1.wlz
3892_wholemount_moderate_3D_1.wlz
3892_wholemount_possible_3D_1.wlz
3892_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:3892_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
future midbrain
detected detected
regionalExpression is at the mid/hindbrain junction and in the dorsal midline of the midbrain.
future hindbrain
detected detected
regionalExpression is in the dorsal midline.
future spinal cord
detected detected
regionalExpression is in the dorsal midline.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2683021
Entity Detected:Wnt1, wingless-related MMTV integration site 1 ( MGI:98953)
Notes:The Wnt1 probe used in this study by Zhou et al., 2003 [PMID:12915301] is described as that originally described by McMahon et al., 1992 [PMID:1534034] . Editors note: McMahon et al. describe three Wnt1 in situ probes (Wnt13'a, Wnt13'b and Wnt15'). It is not specified which was used in this study by Zhou et al.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:C57BL/6
Age:25 Somite no.
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Zhou XH; Brandau O; Feng K; Oohashi T; Ninomiya Y; Rauch U; Fassler R, 2003 [PMID:12915301] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/0092-8674(92)90222-X] [ PMID:1534034] McMahon AP, Joyner AL, Bradley A, McMahon JA 1992 The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell (69):581-95
 [ doi:10.1016/0092-8674(92)90222-X] [ PMID:1534034] McMahon AP, Joyner AL, Bradley A, McMahon JA 1992 The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell (69):581-95
Links:MGI:2683022 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI