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EMAGE:768

Olig2 oligodendrocyte transcription factor 2 ( MGI:1355331)
TS20 (12.5 dpc)
in situ hybridisation

Data Images
EMAGE:768
Fig 7F Corbin et al, 2003 [PMID:12930780] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image annotation: Arrow points to the dorsal limit of expression.
Expression Pattern Description
Spatial Annotation:
EMAGE:768EMAGE:768Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
768_voxel_strong_3D_1.wlz
768_voxel_moderate_3D_1.wlz
768_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:768_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
telencephalon
detected detected
regionalExpression in VZ of the lateral ganglionic eminence (LGE) and medial ganglionic eminence (MGE).
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2148197
Entity Detected:Olig2, oligodendrocyte transcription factor 2 ( MGI:1355331)
Notes:The Olig2 (Olg-2) probe used in this study by Corbin et al., 2001 [PMID:12930780] is defined as that described by Lu et al, 2000 [PMID:10719888] ie: "Antisense riboprobe for Olg-2 was generated by linearization of the plasmid pRBRAH16 (ATCC) with EcoRI and subsequent incubation with T3 RNA polymerase".
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:12.5 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:cryosection
General Information
Authors:Corbin et al, 2003 [PMID:12930780] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.00717] [ PMID:12930780] Corbin JG, Rutlin M, Gaiano N, Fishell G 2003 Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development (130):4895-906
 [ doi:10.1016/S0896-6273(00)80897-1] [ PMID:10719888] Lu QR, Yuk D, Alberta JA, Zhu Z, Pawlitzky I, Chan J, McMahon AP, Stiles CD, Rowitch DH 2000 Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron (25):317-29
Links:MGI:2676250 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI